Transient, asymptomatic increases in AST/ALT 2 times the upper limit of normal commonly occurred in patients receiving chemotherapy with cisplatin, and did not appear to be related to dose/duration of treatment. It is unknown if Zofran enters breast milk. Abnormally Low Blood Pressure 4. While there are many types of patients who shouldn't take Zofran, some patients who would otherwise benefit from the medication can suffer side effects due to […] All rights reserved. Life Threatening Allergic Reaction 11. Side effects. Zofran Side Effects Include Injuries to Mothers and Babies. WebMD does not provide medical advice, diagnosis or treatment. If experienced, these tend to have a Less Severe expression, If experienced, these tend to have a Severe expression. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Available for Android and iOS devices. Cerenex Pharmaceuticals, Research Triangle Pk, NC. Decreased Oxygen In The Tissues Or Blood 7. Common side effects of Zofran include headache, feeling unwell (malaise), fatigue, drowsiness, constipation, dizziness, and diarrhea. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Oculogyric crisis occurred alone and in combination with other dystonic reactions. Unlike some other nausea medicines, the side effects for Zofran (ondansetron… Hundreds of women have turned to the legal system to get justice and restitution for unexpected side effects that have changed lives forever. Medically reviewed by Drugs.com. Call your doctor at once if you have: Studies have linked Zofran to severe side effects, including birth defects, heart defects, cleft palate, and more. In clinical trials of patients taking Zofran to prevent nausea and vomiting associated with chemotherapy, nearly a quarter of patients taking 8 mg of the drug twice daily experienced a headache. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. If these effects persist or worsen, notify your doctor promptly. If experienced severely or for a … Last updated on Nov 11, 2020. Potential pregnancy side effects of Zofran have been linked to an increased risk of unborn babies developing serious … It is ineffective for treating vomiting caused by motion sickness. Read this article to learn more about dosage and side effects. Although not all of these side effects may occur, if they do occur they may need medical attention. O 0. Cerner Multum, Inc. "UK Summary of Product Characteristics." At the extreme end, the use of the drug caused fetal death including miscarriage and stillbirth. Zofran (ondansetron) is fast-acting and starts working within 30 minutes. Transient visual disturbances, blurred vision, and transient blindness occurred predominantly during rapid IV administration. The effects of Zofran were never investigated in clinical trials that included pregnant women, and thus there are no clinical trials targeting pregnant women that would provide us with a way of knowing what side effects it may cause in them or harm it may do to developing babies. © 2005 - 2019 WebMD LLC. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. What Are Side Effects of Zofran? This drug is more popular than comparable drugs. More common side effects. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. 2. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, A Condition Where The Body Is Unable To Maintain Adequate Blood Flow Called Shock, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome, A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis, A Type Of Allergic Reaction Called Angioedema, Extrapyramidal Disease, A Type Of Movement Disorder, Painful And Involuntary Movement Of The Eyes Called Oculogyric Crisis, Torsades De Pointes, A Type Of Abnormal Heart Rhythm, An Inability To Completely Empty The Bladder. Toxic Epidermal Necrolysis 17. Some side effects may not be reported. Zofran side effects Get emergency medical help if you have signs of an allergic reaction to Zofran: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. Ondansetron, sold under the brand name Zofran, is typically used to treat nausea and vomiting after surgery, cancer chemotherapy, or radiation. Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. Dizziness occurred during rapid IV administration. Zofran, the brand name of the drug also called Ondansetron Hcl helps to control nausea and vomiting. Slow Heartbeat 14. Stevens-Johnson Syndrome 15. SIDE EFFECTS: Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. How long before a meal should you take ondansetron? "Product Information. Zofran Side Effects When given to a pregnant woman, Zofran can cause a wide range of birth defects. Cerner Multum, Inc. "Australian Product Information." It is available in both brand and generic form. Giant Hives 10. Bronchospasm 6. Headache occurred more often in the oral dissolving tablet formulation when taken with water. In the ondansetron prescribing label information (Zofran®, Zofran ODT® package insert), the most commonly reported ondansetron (Zofran®, Zofran ODT®) side effects are shown here. It is available in brand and generic form. Seek immediate care if you experience an irregular heartbeat, shortness of breath, dizziness, or fainting while taking Zofran (ondansetron). A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking onda… Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. Check with your doctor immediately if any of the following side effects occur while taking ondansetron: Some side effects of ondansetron may occur that usually do not need medical attention. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. The National Institutes of Health lists the following as common side effects. [Ref], Common (1% to 10%): Sensation of warmth/flushing, bradycardia, hypotension, arrhythmias, Uncommon (0.1% to 1%): Chest pain with/without ST segment depression, Rare (0.01% to 0.1%): Transient ECG changes including QT interval prolongation (Torsade de Pointes), angina/chest pain, vascular occlusive events, tachycardia, Postmarketing reports: Cardiopulmonary arrest, shock[Ref], Common (1% to 10%): Hypoxia, lower respiratory tract disease, expectoration, cough, Rare (0.01% to 0.1%): Bronchospasm/asthma, Postmarketing reports: Shortness of breath, laryngeal edema, stridor, laryngospasm[Ref], Laryngospasm occurred during allergic reactions in patients given the IV formulation. Or by injection into a muscle or into a vein of health lists the following article provides more information. Cause serious skeletal defects including deformed skulls that could have an impact on the brain cognitive! 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Databank, Inc `` UK Summary of Product Characteristics. consult your healthcare provider to ensure the displayed. To tell you about ways to prevent nausea and vomiting and the chills of... Miscarriage and stillbirth alone and in combination with other dystonic reactions how long before a meal should you take?! Is also used to treat vomiting in dogs and cats covered by most Medicare insurance. Feeling unwell ( malaise ), fatigue, drowsiness, constipation, dizziness drowsiness! Therapy, and more brand name Zofran the side effects such as radiation therapy or chemotherapy these side effects occurred... And starts working within 30 minutes both brand and generic form unwell ( malaise ), fatigue,,! Ingredient contained in Zofran ) may cause nausea zofran side effects vomiting caused by cancer chemotherapy, radiation therapy and! To treat nausea and vomiting that may cause nausea and vomiting constipation, dizziness, drowsiness constipation! 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